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BRD4/CK2-IN-1

Product Specifications

CAS Number

2756851-99-5

Target

Apoptosis|||Casein Kinase|||Epigenetic Reader Domain|||Autophagy

Related Pathways

Chromatin/Epigenetic|||Metabolism|||Autophagy|||Stem Cells|||Apoptosis

Purity

0.9902

Bioactivity

BRD4/CK2-IN-1 is a small molecule inhibitor targeting BRD4 and CK2, with an IC50 of 180nM for BRD4 and 230nM for CK2. It inhibits the proliferation of MDA-MB-231 and MDA-MB-468 cells, inducing apoptosis and autophagy-related cell death. It can be used in triple-negative breast cancer research.

Smiles

O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=CC(OCC(=O)NC4=CC=C(C(Cl)=C4)N5CCN(C)CC5)=CC3

Molecular Formula

C29H30ClN5O5

Molecular Weight

564.03

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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