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Trimetrexate glucuronate

Product Specifications

CAS Number

82952-64-5

Target

Antibacterial, Antifolate, Others

Related Pathways

Cell Cycle/Checkpoint, Others, Microbiology/Virology

Bioactivity

Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, blocking the synthesis of purine nucleotides and thymidylic acid, therefore affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects.

Smiles

O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O.COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

Molecular Formula

C25H33N5O10

Molecular Weight

563.564

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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