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FAK-IN-2

Product Specifications

Target

FAK, Apoptosis, Others

Related Pathways

Cytoskeletal Signaling, Angiogenesis, Others, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

FAK-IN-2 is a potent, orally active adherens spot kinase (FAK) inhibitor (IC50: 35 nM) that exhibits antitumour effects. FAK-IN-2 covalently inhibits FAK autophosphorylation in a dose-dependent manner and also inhibits tumour cell formation and migration and induces apoptosis.

Molecular Formula

C28H31ClN8O3

Molecular Weight

563.05

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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