GSK3739936
Product Specifications
CAS Number
1803444-21-4
Target
Others, HIV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Others
Bioactivity
GSK3739936 is a potent inhibitor of HIV-1 allosteric integrase (IC50: 11.1 nM, EC50: 1.7 nM) . GSK3739936 is also a weak inhibitor of CYP with an IC50 >24.3 μM. It has good pharmacokinetic properties with rapid absorption, low to moderate clearance and good oral bioavailability.
Smiles
[C@@H](OC(C)(C)C)(C(O)=O)C1=C(C(=C(C)N=C1C)C2=CC=C(OCCC3=CC=C(F)C=C3)C=C2)N4CCC(C)(C)CC4
Molecular Formula
C34H43FN2O4
Molecular Weight
562.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL703208V 500 µL Each
Slc31a2 Rat shRNA Lentiviral Particle (Locus ID 298091)
Sign In for Pricing
View Details