Multi-kinase-IN-2
Product Specifications
CAS Number
2095628-21-8
Target
Others|||Apoptosis|||FGFR|||VEGFR|||Akt|||PDGFR|||c-Kit|||Src
Related Pathways
Apoptosis|||Angiogenesis|||Others|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Bioactivity
Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFR?/?, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly attenuates phosphorylation of AKT and ERK proteins, induces apoptosis and has anticancer effects.
Smiles
C(\NC1=CC=C(C=C1)N2C(CN3CCN(C)CC3)=CC=C2C)(=C\4/C=5C(NC4=O)=CC(C(OC)=O)=CC5)/C6=CC=CC=C6
Molecular Formula
C34H35N5O3
Molecular Weight
561.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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