(R) - (-) -Gossypol acetic acid
Product Specifications
CAS Number
866541-93-7
Target
Autophagy, Bcl-2 Family
Related Pathways
Apoptosis, Autophagy
Purity
0.995
Bioactivity
(R) - (-) -Gossypol acetic acid (AT101 acetate), the R- (-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 μM, 0.48 μM, and 0.18 μM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]
Smiles
CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
Molecular Formula
C30H30O8·C2H4O2
Molecular Weight
578.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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MBS6167541-01 0.1 mL
ARX (aristaless Related Homeobox, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS) (APC)
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View Details MBS6167541-02 5x 0.1 mL
ARX (aristaless Related Homeobox, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS) (APC)
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