(R) - (-) -Gossypol acetic acid
Product Specifications
CAS Number
866541-93-7
Target
Autophagy|||Bcl-2 Family
Related Pathways
Apoptosis|||Autophagy
Purity
0.995
Bioactivity
(R) - (-) -Gossypol acetic acid (AT101 acetate), the R- (-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 ?M, 0.48 ?M, and 0.18 ?M, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]
Smiles
CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
Molecular Formula
C30H30O8·C2H4O2
Molecular Weight
578.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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