(R) - (-) -Gossypol acetic acid

Product Specifications

CAS Number

866541-93-7

Target

Autophagy|||Bcl-2 Family

Related Pathways

Apoptosis|||Autophagy

Purity

0.995

Bioactivity

(R) - (-) -Gossypol acetic acid (AT101 acetate), the R- (-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 ?M, 0.48 ?M, and 0.18 ?M, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]

Smiles

CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O

Molecular Formula

C30H30O8·C2H4O2

Molecular Weight

578.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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