PI3K-IN-29
Product Specifications
CAS Number
2768005-77-0
Target
Others, Akt, PI3K
Related Pathways
Cytoskeletal Signaling, Others, PI3K/Akt/mTOR signaling
Bioactivity
PI3K-IN-29, a potent inhibitor of PI3K, exhibits substantial inhibition capabilities against U87MG, HeLa, and HL60 cells, with IC50 values of 0.264, 2.04, and 1.14 μM, respectively. It effectively blocks the PI3K/Akt signaling pathway by preventing the PI3K-catalyzed phosphorylation of Akt [1].
Smiles
N(S(=O)(=O)C1=CC=CC=C1)C2=CC(C3=CC=4C(=CN=NC4C=C3)C=5C=NC(=NC5)N6CCOCC6)=CN=C2Cl
Molecular Formula
C27H22ClN7O3S
Molecular Weight
560.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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