MU1656
Product Specifications
CAS Number
2766698-38-6
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9692
Bioactivity
MU1656 is a potent and selective inhibitor of histone methyltransferase DOT1L (IC50 = 2 nM), a key epigenetic regulatory protein involved in the development of cancers such as hematologic malignancies, thus MU1656 was able to significantly inhibit the proliferation of cancer cells and induce apoptosis.
Smiles
O[C@H]1[C@H](C=2N3C(=CC2)C(N)=NC=N3)C[C@H](CN(C(C)C)[C@H]4C[C@@H](CCC=5NC=6C(N5)=CC=C(C(C)(C)C)C6)C4)[C@H]1O
Molecular Formula
C32H45N7O2
Molecular Weight
559.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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