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B026

Product Specifications

CAS Number

2379416-48-3

Target

Others, Histone Acetyltransferase

Related Pathways

Others, Chromatin/Epigenetic

Bioactivity

B026 is a selective, orally active inhibitor of p300/CBP histone acetyltransferase (p300/CBP HAT) that acts on p300 (IC50: 1.8 nM) and CBP (IC50: 9.5 nM) . b026 exhibits anticancer effects on androgen receptor positive (AR+) prostate cancer cells.

Smiles

O=C1[C@]2(C=3C(CC2)=CC(=CC3)C4=CN(C)N=C4)NC(=O)N1CC(=O)N5[C@H](C(F)(F)F)COC=6C(C5)=CC(F)=CC6

Molecular Formula

C27H23F4N5O4

Molecular Weight

557.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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