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BCR-ABL-IN-4

Product Specifications

CAS Number

2669790-59-2

Target

Others, Bcr-Abl

Related Pathways

Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others

Bioactivity

BCR-ABL-IN-4 is a BCR-ABL inhibitor exhibiting anticancer activity with an inhibitory effect on cancer cell growth, specifically on K562 cells (IC50: 0.67 nM) and BCR-ABL T315I-transfected Ba/F3 cells (IC50: 16 nM) .

Smiles

C(NC1=CC=C(OC(Cl)(F)F)C=C1)(=O)C2=CC(=C(N=C2)N3C[C@H](O)CC3)C=4C=C5C(=NC4)CN(C5=O)C6CC6

Molecular Formula

C27H24ClF2N5O4

Molecular Weight

555.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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