BCR-ABL-IN-4
Product Specifications
CAS Number
2669790-59-2
Target
Others, Bcr-Abl
Related Pathways
Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others
Bioactivity
BCR-ABL-IN-4 is a BCR-ABL inhibitor exhibiting anticancer activity with an inhibitory effect on cancer cell growth, specifically on K562 cells (IC50: 0.67 nM) and BCR-ABL T315I-transfected Ba/F3 cells (IC50: 16 nM) .
Smiles
C(NC1=CC=C(OC(Cl)(F)F)C=C1)(=O)C2=CC(=C(N=C2)N3C[C@H](O)CC3)C=4C=C5C(=NC4)CN(C5=O)C6CC6
Molecular Formula
C27H24ClF2N5O4
Molecular Weight
555.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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