KRAS G12C inhibitor 25
Product Specifications
CAS Number
2734060-73-0
Target
Others, Kras, Ras
Related Pathways
GPCR/G Protein, Others, MAPK
Bioactivity
KRAS G12C inhibitor 25 is an inhibitor of KRAS G12C. KRAS G12C inhibitor 25 inhibits the SOS1-assisted GDP/GTP exchange activity of KRAS-G12C mutants with an IC50 value of 0.48 nM.
Smiles
O(C[C@H]1N(C)CCC1)C2=NC(=C3C(C[C@@H](CC3)N4C=5C(CCC4)=CC=CC5)=N2)N6C[C@H](CC#N)N(C(C=C)=O)CC6
Molecular Formula
C32H41N7O2
Molecular Weight
555.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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