HGGPPS-IN-2
Product Specifications
CAS Number
2241547-82-8
Target
Others, Apoptosis
Related Pathways
Apoptosis, Others
Bioactivity
HGGPPS-IN-2 is an analogue of C-2 substituted thienopyrimidinyl bisphosphonates (C2-ThP-BPs) and is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS) . hGGPPS-IN-2 targets multiple myeloma (MM) cells, induces selective apoptosis, and shows anti-myeloma effects in vivo. It has shown anti-myeloma effects in vivo.
Smiles
N(C(P(=O)(O)O)P(=O)(O)O)C1=C2C(=NC(=N1)C3=CC(NC(NC4=CC=C(F)C=C4)=O)=CC=C3)SC=C2
Molecular Formula
C20H18FN5O7P2S
Molecular Weight
553.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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