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HGGPPS-IN-2

Product Specifications

CAS Number

2241547-82-8

Target

Others, Apoptosis

Related Pathways

Apoptosis, Others

Bioactivity

HGGPPS-IN-2 is an analogue of C-2 substituted thienopyrimidinyl bisphosphonates (C2-ThP-BPs) and is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS) . hGGPPS-IN-2 targets multiple myeloma (MM) cells, induces selective apoptosis, and shows anti-myeloma effects in vivo. It has shown anti-myeloma effects in vivo.

Smiles

N(C(P(=O)(O)O)P(=O)(O)O)C1=C2C(=NC(=N1)C3=CC(NC(NC4=CC=C(F)C=C4)=O)=CC=C3)SC=C2

Molecular Formula

C20H18FN5O7P2S

Molecular Weight

553.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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