XP-524
Product Specifications
CAS Number
2344825-52-9
Target
Others, Ras, Epigenetic Reader Domain, Kras
Related Pathways
Chromatin/Epigenetic, Others, MAPK
Bioactivity
XP-524 is a potent inhibitor of BET and EP300. XP-524 has significant tumouricidal effects in vivo, preventing KRAS-induced tumour transformation in vivo and prolonging survival in two aggressive PDAC transgenic mouse models. XP-524 also enhances the expression of its own peptide and recruitment of tumour cells to cytotoxic T lymphocytes. XP-524 has shown potential for research in pancreatic ductal adenocarcinoma (PDAC) .
Smiles
C(C)(N1C=2C(=C(NS(CC)(=O)=O)C=C(C2)C=3C4=C(N(C)C3)C(=O)NC=C4)C=C1)(C5=CC=CC=N5)C6=CC=CC=N6
Molecular Formula
C30H28N6O3S
Molecular Weight
552.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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