SOS1-IN-14
Product Specifications
CAS Number
2793405-20-4
Target
Ras, Others, Kras
Related Pathways
MAPK, GPCR/G Protein, Others
Bioactivity
SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM) . sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.
Smiles
[H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C1(CC1)C#N
Molecular Formula
C29H29F3N6O2
Molecular Weight
550.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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