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MicroRNA-21-IN-1

Product Specifications

CAS Number

2848720-31-8

Target

Apoptosis, MicroRNA, Others

Related Pathways

Others, Chromatin/Epigenetic, Apoptosis

Bioactivity

MicroRNA-21-IN-1 (compound 7A) is an effective inhibitor of microRNA with antiproliferative effects on Hela and HCT-116 cells, showing IC50 values of 5.5 μM and 2.8 μM, respectively. It also induces apoptosis in Hela cells and increases the expression of PTEN, EGR1, and SLIT2, which are functional targets downstream of microRNA-21. This compound holds potential for anticancer research [1].

Smiles

C(C)N1C=2C(C(=O)C(C(NC3=CC=C(C(NCCN4CCCCC4)=O)C=C3)=O)=C1)=CC(F)=C(C2)N5CCNCC5

Molecular Formula

C30H37FN6O3

Molecular Weight

548.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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