MicroRNA-21-IN-1
Product Specifications
CAS Number
2848720-31-8
Target
Apoptosis|||MicroRNA|||Others
Related Pathways
Others|||Chromatin/Epigenetic|||Apoptosis
Bioactivity
MicroRNA-21-IN-1 (compound 7A) is an effective inhibitor of microRNA with antiproliferative effects on Hela and HCT-116 cells, showing IC50 values of 5.5 ?M and 2.8 ?M, respectively. It also induces apoptosis in Hela cells and increases the expression of PTEN, EGR1, and SLIT2, which are functional targets downstream of microRNA-21. This compound holds potential for anticancer research [1].
Smiles
C(C)N1C=2C(C(=O)C(C(NC3=CC=C(C(NCCN4CCCCC4)=O)C=C3)=O)=C1)=CC(F)=C(C2)N5CCNCC5
Molecular Formula
C30H37FN6O3
Molecular Weight
548.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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