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TRβ agonist 1

Product Specifications

CAS Number

2770681-85-9

Target

Others, Thyroid hormone receptor (THR)

Related Pathways

Others, Endocrinology/Hormones

Bioactivity

TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM. It is useful in the research of dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH) [1].

Smiles

O(C)C=1C2=C(C(O)=C(C(NCC(O)=O)=O)N1)C=CC(OC3=C(C)C=C(C(=O)C4=CC(OC)=CC(F)=C4)C=C3C)=C2

Molecular Formula

C29H25FN2O8

Molecular Weight

548.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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