CCT373566
Product Specifications
CAS Number
2378853-66-6
Target
Others|||Molecular Glues|||Bcl-2 Family
Related Pathways
Others|||Apoptosis|||PROTAC
Bioactivity
CCT373566 is a potent, orally active degrader of the transcriptional repressor BCL6 (IC50: 2.2 nM) . CCT373566 exhibits significant anti-proliferative effects in vitro and reduces tumour growth in vivo.
Smiles
O=C1C2=C(C=3C(N1C)=CC=C(NC4=NC(=NC=C4Cl)N5C[C@@H](C)C[C@@H](O)C5)C3)N[C@H](C(F)(F)CO2)C6CC6
Molecular Formula
C26H29ClF2N6O3
Molecular Weight
547
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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