BSJ-01-175
Product Specifications
CAS Number
2227392-55-2
Target
Others, CDK
Related Pathways
Cell Cycle/Checkpoint, Others
Bioactivity
BSJ-01-175 is a selective and potent covalent inhibitor of CDK12/13. BSJ-01-175 is significantly selective for cancer cells, exhibits potent inhibition of phosphorylated RNA polymerase II, and significantly downregulates CDK12 target genes.
Smiles
ClC=1C(C=2C=3C(NC2)=CC=CC3)=NC(N[C@H]4C[C@H](OC5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)CCC4)=NC1
Molecular Formula
C30H33ClN6O2
Molecular Weight
545.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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