RET-IN-19
Product Specifications
CAS Number
2484919-71-1
Target
Others|||c-RET|||Aurora Kinase|||c-Fms|||MAPK|||EGFR
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Others|||MAPK|||Angiogenesis|||Cell Cycle/Checkpoint
Bioactivity
RET-IN-19 is a potent inhibitor of RET and exhibits anticancer effects on RET-wt (IC50: 6.8 nM) and RET V804M (IC50: 13.51 nM) .RET-IN-19 can be used to study non-small cell lung cancer (NSCLC) .
Smiles
N(C1=C2C(NC(=C2)C3=CC=C(S(C)(=O)=O)C=C3)=NC=N1)C4=CC=C(CC(NC=5C=C(C(C)(C)C)ON5)=O)C=C4
Molecular Formula
C28H28N6O4S
Molecular Weight
544.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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