Filgotinib maleate
Product Specifications
CAS Number
1802998-75-9
Target
Others, HIV Protease, JAK
Related Pathways
Chromatin/Epigenetic, Microbiology/Virology, Tyrosine Kinase/Adaptors, Others, Proteases/Proteasome, Stem Cells, Angiogenesis, JAK/STAT signaling
Bioactivity
Filgotinib (maleate) is a selective, orally active JAK1 inhibitor that effectively inhibits the activity of JAK1 (IC50: 10 nM), JAK2 (IC50: 28 nM), JAK3 (IC50: 810 nM) and TYK2 (IC50: 116 nM) . maleate) can be used to study rheumatoid arthritis (RA) and Crohn's disease.
Smiles
OC(=O)\C=C/C(O)=O.O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
Molecular Formula
C25H27N5O7S
Molecular Weight
541.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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