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AMG 900

Product Specifications

CAS Number

945595-80-2

Target

P38 MAPK, Aurora Kinase, Tyrosine Kinases

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, MAPK, Tyrosine Kinase/Adaptors

Purity

0.9951

Bioactivity

AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38α, Tyk2, JNK2, Met, and Tie2. [Phase 1].

Smiles

Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12

Molecular Formula

C28H21N7OS

Molecular Weight

503.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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