AMG 900
Product Specifications
CAS Number
945595-80-2
Target
P38 MAPK, Aurora Kinase, Tyrosine Kinases
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, MAPK, Tyrosine Kinase/Adaptors
Purity
0.9951
Bioactivity
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38α, Tyk2, JNK2, Met, and Tie2. [Phase 1].
Smiles
Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12
Molecular Formula
C28H21N7OS
Molecular Weight
503.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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