PDZ1i
Product Specifications
CAS Number
2083618-79-3
Target
Others, EGFR, FAK, MMP
Related Pathways
Others, Proteases/Proteasome, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, JAK/STAT signaling
Bioactivity
PDZ1i is a potent MDA-9/Syntenin-specific inhibitor that crosses the blood-brain barrier. PDZ1i inhibits key GBM (glioblastoma multiforme) signaling, including FAK and EGFRvIII, and reduces MMP secretion.
Smiles
O=C1N2C(NC3=C1CCC3)=NC(C(NC4=C(C)C=C(NC(CCC=5OC(=NN5)C6=CC=CC=C6)=O)C(C)=C4)=O)=N2
Molecular Formula
C28H26N8O4
Molecular Weight
538.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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