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PND-1186 hydrochloride

Product Specifications

CAS Number

1356154-94-3

Target

FAK, Others, Apoptosis

Related Pathways

Others, Angiogenesis, Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

Bioactivity

PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible, and potent FAK inhibitor (IC50: 1.5 nM) that can selectively induce apoptosis in tumor cells.

Smiles

Cl.CNC(=O)c1ccccc1Nc1cc(Nc2ccc(cc2OC)N2CCOCC2)ncc1C(F)(F)F

Molecular Formula

C25H27ClF3N5O3

Molecular Weight

537.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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