ACT-660602
Product Specifications
CAS Number
1646267-59-5
Target
Others, CXCR
Related Pathways
Others, Autophagy, GPCR/G Protein, Immunology/Inflammation
Bioactivity
ACT-660602 is an orally active chemokine receptor CXCR3 antagonist (IC50: 204 nM) that inhibits T cell migration and has demonstrated significant efficacy in an in vivo model of acute lung injury. It is useful for studying autoimmune diseases.
Smiles
C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F
Molecular Formula
C20H20F6N8OS
Molecular Weight
534.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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