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FGFR4-IN-11

Product Specifications

CAS Number

2396664-85-8

Target

Others, FGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Others

Bioactivity

FGFR4-IN-11 is a selective, potent, covalently bound FGFR4 inhibitor (IC50: 2.1 nM) . FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and exhibits anticancer effects.

Smiles

C(=O)(C=1C=2C(=NC(NC3=C(NC(C=C)=O)C=C(C=C3)N4CCOCC4)=CC2)NC1)C5=CC(OC)=CC(OC)=C5

Molecular Formula

C29H29N5O5

Molecular Weight

527.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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