HF51116
Product Specifications
CAS Number
2177311-29-2
Target
CXCR|||Others
Related Pathways
Autophagy|||Others|||GPCR/G Protein|||Immunology/Inflammation
Bioactivity
HF51116 is a potent antagonist of CXCR4 that significantly inhibits SDF-1?-induced cell migration, calcium mobilization, and CXCR4 internalization. It also prevents HIV-1 infection utilizing CXCR4. HF51116 has shown investigational potential for HIV-1 infection, hematopoietic stem cell mobilization, and cancer metastasis.
Smiles
C(NC([C@H](NCC1=CC=CC=N1)CCCNC(=N)N)=O)C2=CC=C(CNCCCNC3CCCCC3)C=C2
Molecular Formula
C29H46N8O
Molecular Weight
522.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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