γ-Secretase modulator 11 hydrochloride
Product Specifications
CAS Number
2434630-30-3
Target
Others|||Gamma-secretase
Related Pathways
Neuroscience|||Stem Cells|||Others|||Proteases/Proteasome
Bioactivity
?-Secretase modulator 11 hydrochloride is a potent, orally active ?-secretase modulator (IC50: 0.029 ?M) . ?-Secretase modulator 11 hydrochloride significantly reduces brain A?42 levels and rescues the cognitive deficits exhibited by AD model mice. ?-Secretase modulator 11 hydrochloride has shown research potential in Alzheimer's disease.
Smiles
Cl.CNC(=O)c1ccc(cn1)-c1c(C)nc2c(OCc3ccc(cc3F)-c3ccc(F)cc3)cccn12
Molecular Formula
C28H23ClF2N4O2
Molecular Weight
520.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
225104-01 50 µL
PKLR (EC 2.7.1.40, KPYR_HUMAN, L-PK, Pk-1, PK1, PKL, Pklg, Pklr, PKR, PKRL, Pyruvate Kinase 1, Pyruvate Kinase Isozymes R/L, Pyruvate Kinase liver and blood Cell, Pyruvate Kinase liver and RBC, Pyruvate Kinase liver and red blood Cell, Pyruvate Kinase liver Type, Pyruvate Kinase Type L, Pyruvate Kinase, red Cell Type, R Type/L Type Pyruvate Kinase, R-PK, R-Type/L-Type Pyruvate Kinase, Red Cell/liver Pyruvate Kinase, RPK) discontinued
Ask
View Details 225104-02 100 µL
PKLR (EC 2.7.1.40, KPYR_HUMAN, L-PK, Pk-1, PK1, PKL, Pklg, Pklr, PKR, PKRL, Pyruvate Kinase 1, Pyruvate Kinase Isozymes R/L, Pyruvate Kinase liver and blood Cell, Pyruvate Kinase liver and RBC, Pyruvate Kinase liver and red blood Cell, Pyruvate Kinase liver Type, Pyruvate Kinase Type L, Pyruvate Kinase, red Cell Type, R Type/L Type Pyruvate Kinase, R-PK, R-Type/L-Type Pyruvate Kinase, Red Cell/liver Pyruvate Kinase, RPK) discontinued
Ask
View Details 