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Palbociclib dihydrochloride

Product Specifications

Target

CDK, Others

Related Pathways

Others, Cell Cycle/Checkpoint

Bioactivity

Palbociclib (PD 0332991) dihydrochloride is an orally active, selective inhibitor of CDK4 (IC50: 11 nM) and CDK6 (IC50: 16 nM), exhibiting anti-proliferative activity and inducing cell cycle arrest in HR-positive and HER2-negative breast cancers and hepatocellular carcinoma studies.

Molecular Formula

C24H31Cl2N7O2

Molecular Weight

520.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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