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Exatecan-amide-cyclopropanol

Product Specifications

CAS Number

2414254-34-3

Target

Others, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Others

Purity

0.98308

Bioactivity

Exatecan-amide-cyclopropanol is an anticancer agent that potently inhibits the proliferation of SK-BR-3 breast cancer cells with an IC50 value of 0.12 nM, and it also suppresses the growth of U87 glioblastoma cells with an IC50 value of 0.23 nM, Exatecan-amide-cyclopropanol demonstrate robust cytotoxic potential across distinct cancer cell lines. Exatecan-amide-cyclopropanol is primarily used in research aimed at understanding DNA-topoisomerase inhibition mechanisms and their therapeutic implications in oncology.

Smiles

CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)C6(O)CC6)c(c3Cn1c2=O)c45

Molecular Formula

C28H26FN3O6

Molecular Weight

519.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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