Exatecan-amide-cyclopropanol
Product Specifications
CAS Number
2414254-34-3
Target
Others, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Others
Purity
0.98308
Bioactivity
Exatecan-amide-cyclopropanol is an anticancer agent that potently inhibits the proliferation of SK-BR-3 breast cancer cells with an IC50 value of 0.12 nM, and it also suppresses the growth of U87 glioblastoma cells with an IC50 value of 0.23 nM, Exatecan-amide-cyclopropanol demonstrate robust cytotoxic potential across distinct cancer cell lines. Exatecan-amide-cyclopropanol is primarily used in research aimed at understanding DNA-topoisomerase inhibition mechanisms and their therapeutic implications in oncology.
Smiles
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)C6(O)CC6)c(c3Cn1c2=O)c45
Molecular Formula
C28H26FN3O6
Molecular Weight
519.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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