LRRK2-IN-4
Product Specifications
CAS Number
2641054-59-1
Target
Others, LRRK2
Related Pathways
Others, Autophagy
Bioactivity
LRRK2-IN-4 is a potent, selective, orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor that crosses the blood-brain barrier with an IC50 value of 2.6 nM. LRRK2-IN-3 has shown investigational potential in [Parkinson's disease].
Smiles
FC1(F)[C@H](C1)N2C(C)=C(NC3=NC4=C(C=N3)C=C(Cl)C(=C4)C5CCN(CC5)[C@]6(C)[C@H](O)COC6)C=N2
Molecular Formula
C25H29ClF2N6O2
Molecular Weight
518.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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