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LRRK2-IN-3

Product Specifications

CAS Number

2641054-60-4

Target

Others|||LRRK2

Related Pathways

Autophagy|||Others

Bioactivity

LRRK2-IN-3 is a potent, selective, orally active LRRK2 inhibitor that crosses the blood-brain barrier with an IC50 value of 0.6 nM in hPBMCs. LRRK2-IN-3 can be used to study Parkinson's disease.

Smiles

FC1(F)[C@@H](C1)N2C(C)=C(NC3=NC4=C(C=N3)C=C(Cl)C(=C4)C5CCN(CC5)[C@@]6(C)[C@@H](O)COC6)C=N2

Molecular Formula

C25H29ClF2N6O2

Molecular Weight

518.99

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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