Domatinostat
Product Specifications
CAS Number
910462-43-0
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair
Purity
0.9974
Bioactivity
Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) . Phase 1.
Smiles
Cn1cc(cn1)-c1ccc(cc1)S(=O)(=O)n1ccc(\C=C\C(=O)Nc2ccccc2N)c1
Molecular Formula
C23H21N5O3S
Molecular Weight
447.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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