Domatinostat

Product Specifications

CAS Number

910462-43-0

Target

Apoptosis|||HDAC

Related Pathways

Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair

Purity

0.9974

Bioactivity

Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 ?M, 1.12 ?M, and 0.57 ?M for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) . Phase 1.

Smiles

Cn1cc(cn1)-c1ccc(cc1)S(=O)(=O)n1ccc(\C=C\C(=O)Nc2ccccc2N)c1

Molecular Formula

C23H21N5O3S

Molecular Weight

447.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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