ATR-IN-18
Product Specifications
CAS Number
2766407-55-8
Target
ATM/ATR|||Others
Related Pathways
Others|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Bioactivity
ATR-IN-18 is an orally active ATR kinase inhibitor (IC50: 0.69 nM) . aTR-IN-18 exhibited anti-proliferative effects in LoVo cells (IC50: 37.34 nM) . aTR-IN-18 showed anti-tumor effects.
Smiles
OC(=O)C(F)(F)F.C[C@@H]1COCCN1c1nc2n(ncc2c2N(CCc12)S(C)(=O)=O)-c1cc[nH]n1
Molecular Formula
C19H22F3N7O5S
Molecular Weight
517.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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