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Dasabuvir sodium

Product Specifications

CAS Number

1132940-11-4

Target

Others, DNA/RNA Synthesis, HCV Protease

Related Pathways

Proteases/Proteasome, Cell Cycle/Checkpoint, Others, Microbiology/Virology, DNA Damage/DNA Repair

Bioactivity

Dasabuvir (ABT-333) sodium is a non-nucleoside hepatitis C virus (HCV) polymerase inhibitor that exhibits inhibition of the RNA-dependent RNA polymerase (RNA polymerase) encoded by the HCV NS5B gene. Dasabuvir sodium inhibited genotype 1a (strain H77) replicon (EC50: 7.7 nM) and 1b (strain Con1) replicon (EC50: 1.8 nM) .

Smiles

[Na+].COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc([N-]S(C)(=O)=O)ccc2c1

Molecular Formula

C26H26N3NaO5S

Molecular Weight

515.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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