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C-Met-IN-10

Product Specifications

CAS Number

2415291-03-9

Target

Others, Apoptosis, c-Met/HGFR

Related Pathways

Apoptosis, Others, Tyrosine Kinase/Adaptors

Bioactivity

C-Met-IN-10 is a potent c-Met kinase inhibitor (IC50: 16 nM) . c-Met-IN-10 inhibits the activity of cancer cells A549, H460 and HT-29, and inhibits A549 cell movement by inhibiting HT-29 cell colony formation, which in turn induces apoptosis in HT-29 and A549 cells. c-Met-IN-10 can be used in anticancer studies. -Met-IN-10 is capable of being used in anticancer studies.

Smiles

O=C1N(N=C(C(NC2=CC(F)=C(OC=3C=C(NC(=O)C4CC4)N=CC3)C=C2)=O)C(=O)N1C)C5=CC=CC=C5

Molecular Formula

C26H21FN6O5

Molecular Weight

516.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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