PF-8380 hydrochloride
Product Specifications
CAS Number
2070015-01-7
Target
Others, PDE
Related Pathways
Others, Metabolism
Bioactivity
PF-8380 hydrochloride is a powerful inhibitor of autotaxin, exhibiting an IC (50) of 2.8 nM in isolated enzyme assays and 101 nM in human whole blood.
Smiles
Cl.Clc1cc(Cl)cc(COC(=O)N2CCN(CCC(=O)c3ccc4[nH]c(=O)oc4c3)CC2)c1
Molecular Formula
C22H22Cl3N3O5
Molecular Weight
514.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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