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(S) -crizotinib

Product Specifications

CAS Number

1374356-45-2

Target

MTH1, Apoptosis, DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis

Purity

0.9989

Bioactivity

(S) -crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.

Smiles

C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

Molecular Formula

C21H22Cl2FN5O

Molecular Weight

450.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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