(S) -crizotinib

1374356-45-2

MTH1, Apoptosis, DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis

0.9989

(S) -crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.

C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

C21H22Cl2FN5O

450.34

Ice Packs

-20°C