(S) -crizotinib
Product Specifications
CAS Number
1374356-45-2
Target
MTH1, Apoptosis, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis
Purity
0.9989
Bioactivity
(S) -crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.
Smiles
C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Molecular Formula
C21H22Cl2FN5O
Molecular Weight
450.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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