FtsZ-IN-1

FtsZ-IN-1 is a potent FtsZ inhibitor with a quinoline ring, exhibiting a strong inhibitory effect on Gram-positive bacteria (MIC: 0.5-8 μg/mL) . It enhances FtsZ polymerization and significantly promotes cell elongation in Bacillus subtilis. FtsZ-IN-1 has low hemolytic toxicity and demonstrates anti-drug-resistant bacterial effects due to its low tendency to induce drug resistance.