EGFR/HER2/TS-IN-2
Product Specifications
CAS Number
2444364-04-7
Target
Others, DNA/RNA Synthesis, EGFR
Related Pathways
Others, Angiogenesis, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, JAK/STAT signaling
Bioactivity
EGFR/HER2/TS-IN-2 is a potent inhibitor of EGFR (IC50: 0.173 μM), HER2 (IC50: 0.125 μM) and TS (IC50: 1.12 μM) . EGFR/HER2/TS-IN-2 exhibited cytotoxic effects on MDA-MB-231 cancer cells (IC50: 1.69 μM) .
Smiles
C(#N)C=1C(=NC(SCC(NC=2SC=3C(N2)=CC=C(C)C3)=O)=NC1C4=CC=CC=C4)N5N=C(C)C=C5C
Molecular Formula
C26H21N7OS2
Molecular Weight
511.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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