Anticancer agent 64
Product Specifications
CAS Number
2387902-92-1
Target
Others, Apoptosis, Caspase, Bcl-2 Family, PARP
Related Pathways
Others, Proteases/Proteasome, Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
Anticancer agent 64 (compound 5m) exhibits potent cytotoxicity against CCRF-CEM cells with an IC50 value of 2.4 μM, induces apoptosis by activating caspase 3 and 7 and causing PARP cleavage, and significantly disrupts mitochondrial membrane potential, thereby contributing to its anticancer efficacy [1].
Smiles
C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C6=C(C5)SC(N)=N6)[H])[H])[H])([C@H](C(C)=C)CC2)[H]
Molecular Formula
C31H46N2O2S
Molecular Weight
510.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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